It is the deadliest single day of protests since the Palestinians began staging weekly border demonstrations on March 30 in an attempt to break an Israeli-Egyptian blockade.
Protesters set tyres on fire, sending thick plumes of black smoke into the air, while the Israeli military accused protesters of trying to break through the border fence and plant a bomb. They also claimed troops had come under fire.
By the, at least 41 Palestinians – including a 14-year-old boy – were killed, while more than 500 were wounded by Israeli gunfire, Palestinian health officials said.
In the West Bank, several thousand people gathered in the centre of Ramallah, while hundreds marched to the Qalandiya crossing on the outskirts of Jerusalem, where protesters threw stones at Israeli troops